Topology of the biomolecular world
July 24 to July 28, 2017
American Institute of Mathematics,
San Jose, California
Gunnar Carlsson and Guowei Wei
This workshop will be devoted to topological
modeling and analysis of biomolecules. A major feature of life sciences in the
21st century is their transformation from phenomenological and descriptive
disciplines to quantitative and predictive ones. Revolutionary opportunities
have emerged for mathematically driven advances in biological research. However,
the emergence of excessive complexity in self-organizing biological systems
poses fundamental challenges to their quantitative description. Dealing with
the connectivity and transformation of different components in a space,
topology provides a dramatic simplification of biomolecular data and sheds
light on drug design, protein folding, organelle function, signaling, gene
regulation networks and topology-function relationship.
Our goal will be to make
further advances in these directions, with three main topics.
- Fundamental topological theories, algorithms and methods underpin recent
advances in understanding the complexity of biomolecular systems. This workshop
catalyzes the development of new topological theories, algorithms and methods
that are potentially applicable to biological science.
- Topological modeling and analysis of biomolecules This workshop provides a
forum to exchange ideas and present topological results related to research in
mathematical biophysics and molecular biosciences. The emphasis is on the use
of topology to accomplish tasks that cannot be achieved by other conventional
- Potential future topics and directions in both topology and its application
to molecular biophysics will be discussed. Synergistic interactions between
mathematicians and biophysics will promote new trends in biology and topology.
Material from the workshop
A list of participants.
The workshop schedule.
A report on the workshop activities.